In supportive periodontal therapy (SPT), biofilm removal plays a pivotal role. In most treatment settings, hand instruments or oscillating scalers are used to fulfill this task. As an alternative, low abrasive airpolishing (LAA) has been developed to make the treatment easy while allowing gentle debridement. Potential harmful effects of airpolishing on oral tissues have been addressed earlier. Nevertheless, data comparing the effect of various low abrasive media on oral soft tissue is rare, as since the inauguration of LAA in 2003, numerous new products such as powders consisting of erythritol, tricalcium phosphate, trehalose, aluminium trioxide, and hydroxyapatite have been introduced. Using live animals or working on human patients in researchtodateleadstoariseincostsandcomplicatesobtaining new knowledge. Scrutinizing animal models instead may facilitate determination of safety and efficacy of new therapies. Among animal tissues, porcine buccal gingiva obtained from abattoirs bears excellent histological resemblance when compared to human oral tissue. Therefore, the intentionofthisstudywastoestablishandevaluatetheusability of a porcine periodontal treatment model for LAA and to histologically evaluate the influence of various modes of instrumentation.